for me thsoe shaped grips hurt my carpel tunnel because pressure on my palm causes it.
I found something similar with grips that had more pronounced wings. I also found that the more pronounced a wing(larger size/harder), the more it it caused my wrists to cant inward (which might be want you want). The most extreme example of this was my CCX stock grips. They initially felt comfortable but would cause intense ulnar nerve issues (ring and little finger) that were felt hours after riding (known as cycling palsy).
Carpal Tunnel is related to the median nerve.
Since I tried many different handlebars and grips this summer, lets go thru a process of calibrating a baseline setup. Since the word ultimate is already taken, lets call this the 'supreme' method. I will insert a smiley here to absolve me
I would initially setup the rotation(clocking) of the handlebars first by eye. As it turns out, this was never what I ended up with in the end. I had a set of thin round grips and would adjust the bars to get even pressure on my hands. Just by rotating the bars, I could go from median nerve pain to ulnar nerve pain. You might also have to adjust shift/brake levers depending on how you ride. I almost always have two fingers resting on the brakes so I always adjust the levers.
Once I got that dialed in I would start playing with grips. I would take many sets on a ride and change them out. I wont go into all the details but the specialized countour grips I ended up was always my favorite. I liked these because the XLARGE grips were alot thicker and thus the grip was softer. This applied to the wings as well. They were just supportive enough for me without compromising hand positions by being too large and had a little give which seemed to distribute the weight more evenly. I had some medium grips which were likely what stefan had on his Vado and they were much harder and just too small for my hands.
The final solution "for me" was to clock the bars such that I had a very slight median pain and then rotate the grips to even out the weight distribution. This took several rides to dial in.
Also note that gloves are designed differently. Perhaps we can be enlightened on the ultimate glove
