I find myself on the other side of this discussion as I do alot of off road climbing at low/medium assist levels where I find myself using the lower range cogs of my 11/50 cassette. There has been some discussion on the boards about chain rubbing on upper chain stays on some bikes similar to mine when in the 50t which isn't a problem for me but last ride I did hear an intermittent consistent slight rub noise and upon inspection I found it was because the rear wheel had gone slightly out of true in one spot and the chain was rubbing on the tire. Easy enough to fix but I hadn't realized just how close it was.
So as I am happy enough with the speed I am able to climb in mode 2/3, of 5, and don't want to up the watts to get out of the larger cogs I decided I want to go to a smaller chainring and aiming for a 34t narrow/wide 104bcd that I have. However it will take one of the Christini adapters to do so and I chose to go with the more standard offset one rather than the fat specific one. This should get me down a few cogs for the most part and really put some low gears on tap for taking it easy on the thighs/quads on long ride climbs and especially on switchbacks where the ability to spin a low gear is key for me to get around them.
I am not concerned about losing speed on flat sections as I think I will still be able to spin out at least 24mph which is fine as I ride with guys that either have no assist or that cut out at 20 anyway. Downhill speeds are not a problem with a 200lb rider on a 60+lb. bike when gravity has its way. I have never experienced any skipping in the 11t and hopefully won't but I will be taking out at least a few links to keep my derailleur attitude the same as it is now.
Edit: Adding elevation profile of typicalish ride.
And yes that min ele is correct as I went over the Cape and down to the beach on a trail. The rest was some road and mostly gated logging road. Saw about 40 elk @33.20. They were laying down in two groups on the logging road staying out of the wind that is going on here today.